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Literature summary extracted from

  • Beyraghdar Kashkooli, A.; van der Krol, A.; Rabe, P.; Dickschat, J.; Bouwmeester, H.
    Substrate promiscuity of enzymes from the sesquiterpene biosynthetic pathways from Artemisia annua and Tanacetum parthenium allows for novel combinatorial sesquiterpene production (2019), Metab. Eng., 54, 12-23 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.1.92 expressed in Nicotiana benthamiana Artemisia annua

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.92 artemisinic aldehyde + NADPH + H+ Artemisia annua
-
 (11R)-dihydroartemisinic aldehyde + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.92 Artemisia annua C5H429
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.92 3beta-hydroxycostunolide + NADPH + H+
-
 Artemisia annua 3beta-hydroxy-dihydroparthenolide + NADP+
-
 ?
1.3.1.92 artemisinic aldehyde + NADPH + H+
-
 Artemisia annua (11R)-dihydroartemisinic aldehyde + NADP+
-
 ?
1.3.1.92 costunolide + NADPH + H+
-
 Artemisia annua dihydrocostunolide + NADP+
-
 ?
1.3.1.92 parthenolide + NADPH + H+ good substrate Artemisia annua dihydroparthenolide + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.92 artemisinic aldehyde DELTA11(13) double bond reductase2
-
 Artemisia annua
1.3.1.92 Dbr2
-
 Artemisia annua

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.92 NADPH
-
 Artemisia annua