Literature summary extracted from

Lawan, N.; Tinikul, R.; Surawatanawong, P.; Mulholland, A.J.; Chaiyen, P.
QM/MM molecular modeling reveals mechanism insights into flavin peroxide formation in bacterial buciferase (2022), J. Chem. Inf. Model., 62, 399-411 .

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.14.3	Vibrio harveyi	P07740 and P07739	P07740 i.e. subunit LuxA, P07739 i.e. subunit LuxB	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.14.3	a long-chain aldehyde + FMNH2 + O2	-	Vibrio harveyi	a long-chain fatty acid + FMN + H2O + hv	-	?

General Information

EC Number	General Information	Comment	Organism
1.14.14.3	metabolism	the enzyme controls the formation of the FMNH-C4a-OO- intermediate via the conserved His44 residue, the steps are: H+ reacts with O2 to generate +OOH. +OOH attacks C4a of FMNH- to generate FMNH-C4a-OOH. H+ is transferred from FMNH-C4a?OOH to His44 to generate FMNH-C4a-OO- while His44 stabilizes FMNH-C4a-OO- by forming a hydrogen bond to an oxygen atom	Vibrio harveyi

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Release 2023.1 (January 2023)