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Literature summary extracted from

  • Kettner, L.; Braun, C.; Seitl, I.; Pross, E.; Fischer, L.
    Production and characterization of a new diamine oxidase from Yarrowia lipolytica (2021), J. Biotechnol., 340, 39-46 .
    View publication on PubMed

Application

EC Number Application Comment Organism
1.4.3.22 food industry degradation of biogenic amines Yarrowia lipolytica

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.4.3.22 homologously recombinantly integrated into the genome of Yarrowia lipolytica PO1f using the CRISPR-Cas9 system for the subsequent production of diamine oxidase in a bioreactor Yarrowia lipolytica

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.22 histamine substrate inhibition at concentrations greater than 12.5 mM Yarrowia lipolytica

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.22 2.3
-
 histamine pH 7.2, 37°C Yarrowia lipolytica

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.22 Yarrowia lipolytica
-
-
-
1.4.3.22 Yarrowia lipolytica PO1f
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.22
-
 Yarrowia lipolytica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.22 agmatine + H2O + O2
-
 Yarrowia lipolytica ?
-
 ?
1.4.3.22 agmatine + H2O + O2
-
 Yarrowia lipolytica PO1f ?
-
 ?
1.4.3.22 cadaverine + H2O + O2
-
 Yarrowia lipolytica 5-aminopentanal + NH3 + H2O2
-
 ?
1.4.3.22 cadaverine + H2O + O2
-
 Yarrowia lipolytica PO1f 5-aminopentanal + NH3 + H2O2
-
 ?
1.4.3.22 histamine + O2 + H2O degrades around 75% of the histamine used in a bioconversion experiment with a food-relevant concentration of 150 mg/l Yarrowia lipolytica (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 histamine + O2 + H2O degrades around 75% of the histamine used in a bioconversion experiment with a food-relevant concentration of 150 mg/l Yarrowia lipolytica PO1f (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 putrescine + H2O + O2
-
 Yarrowia lipolytica 4-aminobutanal + NH3 + H2O2
-
 ?
1.4.3.22 tryptamine + H2O + O2
-
 Yarrowia lipolytica 1H-indol-3-ylacetaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 tryptamine + H2O + O2
-
 Yarrowia lipolytica PO1f 1H-indol-3-ylacetaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 tyramine + H2O + O2
-
 Yarrowia lipolytica 4-hydroxyphenylethanal + NH3 + H2O2
-
 ?
1.4.3.22 tyramine + H2O + O2
-
 Yarrowia lipolytica PO1f 4-hydroxyphenylethanal + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.22 DAO-1
-
 Yarrowia lipolytica

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.4.3.22 40
-
-
 Yarrowia lipolytica

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.4.3.22 7.2
-
 in Tris-HCl buffer (50 mM) with histamine as substrate Yarrowia lipolytica

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.4.3.22 61.89
-
 histamine pH 7.2, 37°C Yarrowia lipolytica