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Literature summary extracted from

  • Eyice, O.e.; Myronova, N.; Pol, A.; Carrion, O.; Todd, J.D.; Smith, T.J.; Gurman, S.J.; Cuthbertson, A.; Mazard, S.; Mennink-Kersten, M.A.; Bugg, T.D.; Andersson, K.K.; Johnston, A.W.; Op den Camp, H.J.; Schaefer, H.
    Bacterial SBP56 identified as a Cu-dependent methanethiol oxidase widely distributed in the biosphere (2018), ISME J., 12, 145-160 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.3.4 Sulfide
-
 Hyphomicrobium sp. VS
1.8.3.4 Sulfide
-
 Methylophaga thiooxydans
1.8.3.4 Sulfide
-
 Ruegeria pomeroyi

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.3.4 periplasm
-
 Ruegeria pomeroyi
-
-
1.8.3.4 periplasm
-
 Methylophaga thiooxydans
-
-
1.8.3.4 periplasm
-
 Hyphomicrobium sp. VS
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.8.3.4 Cu2+ metalloenzyme that requires Cu2+ for enzyme activity. Cu2+ is involved in the redox process of methanethiol oxidation Ruegeria pomeroyi
1.8.3.4 Cu2+ metalloenzyme that requires Cu2+ for enzyme activity. Cu2+ is involved in the redox process of methanethiol oxidation Methylophaga thiooxydans
1.8.3.4 Cu2+ metalloenzyme that requires Cu2+ for enzyme activity. Cu2+ is involved in the redox process of methanethiol oxidation Hyphomicrobium sp. VS

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.8.3.4 46000
-
 SDS-PAGE Hyphomicrobium sp. VS
1.8.3.4 46186
-
 electrospray-ionisation mass spectroscopy Hyphomicrobium sp. VS
1.8.3.4 180000 200000 native gel electrophoresis Hyphomicrobium sp. VS
1.8.3.4 200000
-
 gel filtration Hyphomicrobium sp. VS

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.3.4 methanethiol + O2 + H2O Ruegeria pomeroyi
-
 formaldehyde + hydrogen sulfide + H2O2
-
 ?
1.8.3.4 methanethiol + O2 + H2O Methylophaga thiooxydans
-
 formaldehyde + hydrogen sulfide + H2O2
-
 ?
1.8.3.4 methanethiol + O2 + H2O Hyphomicrobium sp. VS
-
 formaldehyde + hydrogen sulfide + H2O2
-
 ?
1.8.3.4 methanethiol + O2 + H2O Methylophaga thiooxydans DMS010
-
 formaldehyde + hydrogen sulfide + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.3.4 Hyphomicrobium sp. VS
-
-
-
1.8.3.4 Methylophaga thiooxydans C0N434
-
-
1.8.3.4 Methylophaga thiooxydans DMS010 C0N434
-
-
1.8.3.4 Ruegeria pomeroyi Q5LKW0
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.3.4
-
 Hyphomicrobium sp. VS

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.3.4 methanethiol + O2 + H2O
-
 Ruegeria pomeroyi formaldehyde + hydrogen sulfide + H2O2
-
 ?
1.8.3.4 methanethiol + O2 + H2O
-
 Methylophaga thiooxydans formaldehyde + hydrogen sulfide + H2O2
-
 ?
1.8.3.4 methanethiol + O2 + H2O
-
 Hyphomicrobium sp. VS formaldehyde + hydrogen sulfide + H2O2
-
 ?
1.8.3.4 methanethiol + O2 + H2O
-
 Methylophaga thiooxydans DMS010 formaldehyde + hydrogen sulfide + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.8.3.4 homotetramer 4 * 46000, SDS-PAGE Hyphomicrobium sp. VS

Synonyms

EC Number Synonyms Comment Organism
1.8.3.4 MTO
-
 Ruegeria pomeroyi
1.8.3.4 MTO
-
 Methylophaga thiooxydans
1.8.3.4 MTO
-
 Hyphomicrobium sp. VS
1.8.3.4 SBP56
-
 Hyphomicrobium sp. VS