EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.3.4 | CMP-N-acetyl-beta-neuraminate + a type 3 histo-blood group antigen precursor disaccharide | Homo sapiens | - |
an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R + CMP + H+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.3.4 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.3.4 | AsPC-1 cell | - |
Homo sapiens | - |
2.4.3.4 | BxPC-3 cell | - |
Homo sapiens | - |
2.4.3.4 | CAPAN-1 cell | - |
Homo sapiens | - |
2.4.3.4 | CAPAN-2 cell | - |
Homo sapiens | - |
2.4.3.4 | HPAF-2 cell | - |
Homo sapiens | - |
2.4.3.4 | Panc 10.05 cell | - |
Homo sapiens | - |
2.4.3.4 | pancreatic cancer cell | - |
Homo sapiens | - |
2.4.3.4 | SW-1990 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.3.4 | CMP-N-acetyl-beta-neuraminate + a type 3 histo-blood group antigen precursor disaccharide | - |
Homo sapiens | an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R + CMP + H+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.3.4 | beta-galactoside alpha2,3-sialyltransferase | - |
Homo sapiens |
2.4.3.4 | ST3Gal3 | - |
Homo sapiens |
2.4.3.4 | ST3GAL4 | - |
Homo sapiens |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.4.3.4 | malfunction | downregulation of isoforms ST3GAL3 and ST3GAL4 results in a significant decrease in cell migration and invasion as well as E-selectin-dependent adhesion of pancreatic cancer cells. Downregulation of isoforms ST3GAL4 and ST3GAL3 in BxPC-3 and Capan-1 cells reduces sLex expression | Homo sapiens |