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Literature summary extracted from
- Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor alpha-mediated beta-galactoside alpha2,6-sialyltransferase I expression in human hepatocarcinoma cells (2021), Int. J. Biochem. Cell Biol., 137, 106027 .
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 2.4.3.1 | medicine | increased enzyme expression in hepatocellular carcinoma tissues correlates with poor prognosis | Homo sapiens |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 2.4.3.1 | nucleus | - |
Homo sapiens | 5634 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.4.3.1 | CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-R | Homo sapiens | - |
CMP + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-R | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.4.3.1 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.4.3.1 | Hep-G2 cell | - |
Homo sapiens | - |
| 2.4.3.1 | hepatoma cell | - |
Homo sapiens | - |
| 2.4.3.1 | Huh-7 cell | - |
Homo sapiens | - |
| 2.4.3.1 | MHCC97-H cell | - |
Homo sapiens | - |
| 2.4.3.1 | MHCC97-L cell | - |
Homo sapiens | - |
| 2.4.3.1 | SMMC-7721 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.4.3.1 | CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-R | - |
Homo sapiens | CMP + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-R | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 2.4.3.1 | ? | x * 47000, SDS-PAGE | Homo sapiens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 2.4.3.1 | beta-galactoside alpha2,6-sialyltransferase I | - |
Homo sapiens |
| 2.4.3.1 | ST6Gal-I | - |
Homo sapiens |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 2.4.3.1 | Homo sapiens | the expression level of the enzyme is increased in hepatocellular carcinoma tissues. Caveolin-1 upregulates the enyzme expression | up |
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Release 2023.1 (January 2023)
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