Literature summary extracted from

Hammerbacher, A.; Kandasamy, D.; Ullah, C.; Schmidt, A.; Wright, L.P.; Gershenzon, J.
Flavanone-3-hydroxylase plays an important role in the biosynthesis of spruce phenolic defenses against bark beetles and their fungal associates (2019), Front. Plant Sci., 10, 208 .

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.11.9	Picea abies	A0A481V8E6	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.11.9	eriodictyol + 2-oxoglutarate + O2	-	Picea abies	dihydroquercetin + succinate + CO2	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.11.9	F3H	-	Picea abies
1.14.11.9	flavanone-3-hydroxylase	-	Picea abies

Expression

EC Number	Organism	Comment	Expression
1.14.11.9	Picea abies	highly expressed after Endoconidiophora polonica infection	up

General Information

EC Number	General Information	Comment	Organism
1.14.11.9	physiological function	the enzyme plays an important role in the biosynthesis of spruce phenolic defenses against bark beetles and their fungal associates. The enzyme forms a defensive product, taxifolin, which is also a metabolic precursor of another defensive product, catechin, which in turn synergizes the toxicity of taxifolin to the bark beetle associated fungus	Picea abies

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Release 2023.1 (January 2023)