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Literature summary extracted from

  • An, S.; Choi, G.; Ahn, J.
    Biosynthesis of fraxetin from three different substrates using engineered Escherichia coli (2020), Appl. Biol. Chem., 63, 55.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.11.60 expression in Escherichia coli Arabidopsis thaliana
1.14.11.60 expression in Escherichia coli Oryza sativa

Protein Variants

EC Number Protein Variants Comment Organism
1.14.11.60 synthesis synthesis of fraxetin by three distinct routes, from ferulic acid, esculetin, and scopoletin. An Escherichia coli strain harboring S8H synthesizes 84.8 microM fraxetin from 100 microM scopoletin. The other two approaches lead to less than half of this amount Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.60 Arabidopsis thaliana Q9LE86
-
-
1.14.11.60 Oryza sativa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.60 isoscopoletin + 2-oxoglutarate + O2 55% conversion Arabidopsis thaliana fraxetin + succinate + CO2
-
 ?
1.14.11.60 additional information no substrates: esculetin, and scoparone Arabidopsis thaliana ?
-
 ?
1.14.11.60 additional information no substrates: esculetin, isoscopoletin, and scoparone Oryza sativa ?
-
 ?
1.14.11.60 scopoletin + 2-oxoglutarate + O2 84.8% conversion Arabidopsis thaliana fraxetin + succinate + CO2
-
 ?
1.14.11.60 scopoletin + 2-oxoglutarate + O2
-
 Oryza sativa fraxetin + succinate + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.11.60 At3g12900
-
 Arabidopsis thaliana
1.14.11.60 At3g12900
-
 Oryza sativa
1.14.11.60 S8H
-
 Arabidopsis thaliana
1.14.11.60 S8H
-
 Oryza sativa