Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Uchida, H.; Mikami, B.; Yamane-Tanabe, A.; Ito, A.; Hirano, K.; Oki, M.
    Crystal structure of an aldehyde oxidase from Methylobacillus sp. KY4400 (2018), J. Biochem., 163, 321-328 .
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.2.3.1 structure of recombinant aldehyde oxidase at 2.5 A resolution, a narrow funnel leading to the si-face of the isoalloxazine ring of FAD is found. In the molybdenum catalytic centre a tryptophan is situated near the centre instead of the alanine present in other xanthine oxidase family members Methylobacillus sp. KY4400

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.2.3.1 Molybdenum protein contains 0.96 mol of Mo and 0.78 mol of 5'-CMP per mol of enzyme Methylobacillus sp. KY4400

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.3.1 142000
-
 gel filtration Methylobacillus sp. KY4400

Organism

EC Number Organism UniProt Comment Textmining
1.2.3.1 Methylobacillus sp. KY4400 Q84IX9 and Q84IY0 andQ84IX8 Q84IY0 i.e. small subunit AOMS, Q84IX9 i.e. medium subunit AOMM, Q84IX8 i.e. large subunit AOML
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.3.1 acetaldehyde + H2O + O2
-
 Methylobacillus sp. KY4400 acetic acid + H2O2
-
 ?
1.2.3.1 benzaldehyde + H2O + O2
-
 Methylobacillus sp. KY4400 benzoic acid + H2O2
-
 ?
1.2.3.1 butanal + H2O + O2
-
 Methylobacillus sp. KY4400 butyric acid + H2O2
-
 ?
1.2.3.1 formaldehyde + H2O + O2
-
 Methylobacillus sp. KY4400 formic acid + H2O2
-
 ?
1.2.3.1 heptanal + H2O + O2
-
 Methylobacillus sp. KY4400 heptanoic acid + H2O2
-
 ?
1.2.3.1 hexanal + H2O + O2
-
 Methylobacillus sp. KY4400 hexanoic acid + H2O2
-
 ?
1.2.3.1 additional information no substrates: xanthine and N'-methylnicotinamide Methylobacillus sp. KY4400 ?
-
-
1.2.3.1 vanillin + H2O + O2
-
 Methylobacillus sp. KY4400 vanillic acid + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.2.3.1 trimer x * 17000 plus x * 35000 plus x * 83000, SDS-PAGE Methylobacillus sp. KY4400

Synonyms

EC Number Synonyms Comment Organism
1.2.3.1 AOMM
-
 Methylobacillus sp. KY4400

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.3.1 [4Fe-4S]-center presence of a [4Fe-4 S] cluster in the medium subunit Methylobacillus sp. KY4400