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Literature summary extracted from

  • Saitoh, Y.; Katane, M.; Miyamoto, T.; Sekine, M.; Sakamoto, T.; Imai, H.; Homma, H.
    Secreted D-aspartate oxidase functions in C. elegans reproduction and development (2019), FEBS J., 286, 124-138 .
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.1 extracellular in hermaphrodites, DDO3 is secreted from the proximal gonadal sheath cells in a signal peptide-dependent manner and transferred to the oocyte surface. In males, DDO3 is secreted from the seminal vesicle into the seminal fluid in a signal peptide-dependent manner during mating with hermaphrodites. DDO3 is secreted from the cells where it is produced into the body fluid and taken up by scavenger coelomocytes Caenorhabditis elegans
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Organism

EC Number Organism UniProt Comment Textmining
1.4.3.1 Caenorhabditis elegans O01739 isoform DDO3
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.1 coelomocyte DDO3 is secreted from the cells where it is produced into the body fluid and taken up by scavenger coelomocytes Caenorhabditis elegans
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1.4.3.1 additional information in males, DDO3 is secreted from the seminal vesicle into the seminal fluid in a signal peptide-dependent manner during mating with hermaphrodites. In hermaphrodites, DDO3 is secreted from the proximal gonadal sheath cells in a signal peptide-dependent manner and transferred to the oocyte surface Caenorhabditis elegans
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Synonyms

EC Number Synonyms Comment Organism
1.4.3.1 DDO3
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 Caenorhabditis elegans

General Information

EC Number General Information Comment Organism
1.4.3.1 physiological function the isoform responsible for in vivo metabolism of D-glutamate is DDO3, which is also required for normal self-fertility, hatching, and lifespan Caenorhabditis elegans