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Literature summary extracted from

  • Hlinkina, T.; Kastsiuk, S.
    Correlation between nucleotide substitutions in glycerol-3-phosphate oxidase gene, the level of hydrogen peroxide production, and cytotoxicity of Mycoplasma pneumoniae (2020), Cytol. Genet., 54, 18-22 .
No PubMed abstract available

Application

EC Number Application Comment Organism
1.1.3.21 medicine isolation of mutants with decreased or increased production of H2O2 from children and teens with bronchitis and pneumonia diagnoses. Mutant D55H displays 250% increase in H2O2 production and shows increased cytotoxicity to respiratory epithelium cells, mutant H51L displays 50% reduction in H2O2 production and shows decreased cytotoxicity to respiratory epithelium cells Mycoplasma pneumoniae

Protein Variants

EC Number Protein Variants Comment Organism
1.1.3.21 D55H mutant isolated from children and teens with bronchitis and pneumonia diagnoses, mutant displays 250% increase in H2O2 production. Mutant shows increased cytotoxicity to respiratory epithelium cells Mycoplasma pneumoniae
1.1.3.21 H51L mutant isolated from children and teens with bronchitis and pneumonia diagnoses, mutant displays 50% reduction in H2O2 production. Mutant shows decreased cytotoxicity to respiratory epithelium cells Mycoplasma pneumoniae
1.1.3.21 L61V mutant isolated from children and teens with bronchitis and pneumonia diagnoses, mutant displays no change in H2O2 production Mycoplasma pneumoniae

Organism

EC Number Organism UniProt Comment Textmining
1.1.3.21 Mycoplasma pneumoniae A0A0H3DPW7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.3.21 sn-glycerol 3-phosphate + O2
-
 Mycoplasma pneumoniae glycerone phosphate + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.3.21 IhgO
-
 Mycoplasma pneumoniae