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Literature summary extracted from

  • Zhou, S.; Lama, S.; Jiang, J.; Sankaranarayanan, M.; Park, S.
    Use of acetate for the production of 3-hydroxypropionic acid by metabolically-engineered Pseudomonas denitrificans (2020), Biores. Technol., 307, 123194 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.75 expressed in Pseudomonas denitrificans strain ATCC 13867 Chloroflexus aurantiacus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.75 malonate semialdehyde + NADPH + H+ Chloroflexus aurantiacus
-
3-hydroxypropionic acid + NADP+
-
?
1.2.1.75 malonyl-CoA + NADPH + H+ Chloroflexus aurantiacus
-
malonate semialdehyde + CoA + NADP+
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.75 Chloroflexus aurantiacus Q6QQP7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.75 malonate semialdehyde + NADPH + H+
-
Chloroflexus aurantiacus 3-hydroxypropionic acid + NADP+
-
?
1.2.1.75 malonyl-CoA + NADPH + H+
-
Chloroflexus aurantiacus malonate semialdehyde + CoA + NADP+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.75 malonyl-CoA reductase
-
Chloroflexus aurantiacus
1.2.1.75 MCR
-
Chloroflexus aurantiacus

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.75 NADPH dependent on Chloroflexus aurantiacus