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Literature summary extracted from

  • McAllister, K.N.; Bouillaut, L.; Kahn, J.N.; Self, W.T.; Sorg, J.A.
    Using CRISPR-Cas9-mediated genome editing to generate C. difficile mutants defective in selenoproteins synthesis (2017), Sci. Rep., 7, 14672 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.9.3 ATP + selenide + H2O Clostridioides difficile
-
 AMP + selenophosphate + phosphate
-
 ?
2.7.9.3 ATP + selenide + H2O Clostridioides difficile R20291
-
 AMP + selenophosphate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.9.3 Clostridioides difficile
-
-
-
2.7.9.3 Clostridioides difficile R20291
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.9.3 ATP + selenide + H2O
-
 Clostridioides difficile AMP + selenophosphate + phosphate
-
 ?
2.7.9.3 ATP + selenide + H2O
-
 Clostridioides difficile R20291 AMP + selenophosphate + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.9.3 SelD
-
 Clostridioides difficile
2.7.9.3 selenophosphate synthetase
-
 Clostridioides difficile

General Information

EC Number General Information Comment Organism
2.7.9.3 malfunction the selD CRISPR deletion mutant has a growth defect in protein-rich medium and mimicks the phenotype of a generated TargeTron selD mutation Clostridioides difficile
2.7.9.3 physiological function the enzyme is essential for the specific incorporation of selenium into selenoproteins Clostridioides difficile