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Literature summary extracted from

  • Rimmer, M.A.; Nadeau, O.W.; Artigues, A.; Carlson, G.M.
    Structural characterization of the catalytic gamma and regulatory beta subunits of phosphorylase kinase in the context of the hexadecameric enzyme complex (2018), Protein Sci., 27, 485-497 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.19 Calmodulin
-
 Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.19 Ca2+ activates Oryctolagus cuniculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.19 1300000
-
 calculated from amino acid sequence Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.19 ATP + phosphorylase b Oryctolagus cuniculus
-
 ADP + phosphorylase a
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.19 Oryctolagus cuniculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.11.19 phosphoprotein the enzyme is activated by phosphorylation of Ser26 on beta subunit by cAMP-dependent protein kinase Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.19 skeletal muscle
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.19 ATP + phosphorylase b
-
 Oryctolagus cuniculus ADP + phosphorylase a
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.19 hexadecamer 4 * 138400 + 4 * 125200 + 4 * 44700 + 4 * 16700, calculated from amino acid sequence Oryctolagus cuniculus

Synonyms

EC Number Synonyms Comment Organism
2.7.11.19 PhK
-
 Oryctolagus cuniculus

General Information

EC Number General Information Comment Organism
2.7.11.19 metabolism the enzyme phosphorylates and activates glycogen phosphorylase in the cascade activation of glycogenolysis Oryctolagus cuniculus