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Literature summary extracted from

  • Lee, K.; Kim, E.; Kim, G.; Jung, J.; Katayama, S.; Nakamura, S.; Suh, J.
    Biophysical characterization of the domain association between cytosolic A and B domains of the mannitol transporter enzymes IIMtl in the presence and absence of a connecting linker (2016), Protein Sci., 25, 1803-1811 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.197 expressed in Escherichia coli BL21star(DE3) cells Caldanaerobacter subterraneus subsp. tengcongensis

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.197 C384S active site mutant of enzyme domain B Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.197 C395S active site mutant of enzyme domain B Caldanaerobacter subterraneus subsp. tengcongensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.197 [protein]-Npi-phospho-L-histidine + D-mannitol[side 1] Caldanaerobacter subterraneus subsp. tengcongensis
-
 [protein]-L-histidine + D-mannitol 1-phosphate[side 2]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.197 Caldanaerobacter subterraneus subsp. tengcongensis
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.1.197 phosphoprotein
-
 Caldanaerobacter subterraneus subsp. tengcongensis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.197 [protein]-Npi-phospho-L-histidine + D-mannitol[side 1]
-
 Caldanaerobacter subterraneus subsp. tengcongensis [protein]-L-histidine + D-mannitol 1-phosphate[side 2]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.197 enzyme IImtl
-
 Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.197 IIAmtl domain A of mannitol trasnporter enzyme IIMtl Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.197 IIBmtl domain B of mannitol transporter enzyme IIMtl Caldanaerobacter subterraneus subsp. tengcongensis
2.7.1.197 mannitol transporter
-
 Caldanaerobacter subterraneus subsp. tengcongensis