Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Prasanth, K.R.; Chuang, C.; Nagy, P.D.
    Co-opting ATP-generating glycolytic enzyme PGK1 phosphoglycerate kinase facilitates the assembly of viral replicase complexes (2017), PLoS Pathog., 13, e1006689 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.2.3 expressed in Saccharomyces cerevisiae Nicotiana benthamiana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.2.3 cytosol
-
 Nicotiana benthamiana 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.2.3 ADP + 3-phospho-D-glyceroyl phosphate Nicotiana benthamiana
-
 ATP + 3-phospho-D-glycerate
-
 r
2.7.2.3 ATP + 3-phospho-D-glycerate Nicotiana benthamiana
-
 ADP + 3-phospho-D-glyceroyl phosphate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.2.3 Nicotiana benthamiana E5LLE7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.2.3 ADP + 3-phospho-D-glyceroyl phosphate
-
 Nicotiana benthamiana ATP + 3-phospho-D-glycerate
-
 r
2.7.2.3 ATP + 3-phospho-D-glycerate
-
 Nicotiana benthamiana ADP + 3-phospho-D-glyceroyl phosphate
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.7.2.3 PGK1
-
 Nicotiana benthamiana

General Information

EC Number General Information Comment Organism
2.7.2.3 metabolism the enzyme acts as a pro-viral host factor. Tomato bushy stunt virus co-opts the glycolytic ATP-generating phosphoglycerate kinase 1 to facilitate the intracellular assembly of new viral replicase complexes Nicotiana benthamiana