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Literature summary extracted from

  • Liu, J.; Zhou, J.; Xing, D.
    A pivotal role of phosphatidylinositol 3-kinase in delaying of methyl jasmonate-induced leaf senescence (2016), Plant Signal. Behav., 11, e1147642 .
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.137 endosome
-
 Arabidopsis thaliana 5768
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.137 Mg2+ required Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.137 ATP + 1-phosphatidyl-1D-myo-inositol Arabidopsis thaliana
-
 ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.137 Arabidopsis thaliana P42339
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.137 leaf
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.137 ATP + 1-phosphatidyl-1D-myo-inositol
-
 Arabidopsis thaliana ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.137 phosphatidylinositol 3-kinase
-
 Arabidopsis thaliana
2.7.1.137 PI3K
-
 Arabidopsis thaliana
2.7.1.137 PI3K type III
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.137 ATP
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
2.7.1.137 Arabidopsis thaliana downregulation of PI3K activity accelerates leaf senescence induced by methyl jasmonate (MeJA) and suppresses the activation of vacuolar H+-ATPase (VATPase) down

General Information

EC Number General Information Comment Organism
2.7.1.137 malfunction downregulation of PI3K activity accelerates leaf senescence induced by methyl jasmonate (MeJA) and suppresses the activation of vacuolar H+-ATPase (VATPase) Arabidopsis thaliana
2.7.1.137 metabolism PI3K type III plays a vital role in the trafficking of proteins to and from vacuoles. Interactions between VHA-B2 and PI3K are possibly promoted the translocation of VHA-B2 from the TNG to the vacuole and thus improve the assembly of V-ATPase, resulting in increased V-ATPase activity Arabidopsis thaliana
2.7.1.137 physiological function pivotal role of phosphatidylinositol 3-kinase in delaying of methyl jasmonate-induced leaf senescence. Phosphatidylinositol 3-kinase (PI3K) and its product PI3P are involved in plant development and stress responses. PI3K type III plays a vital role in the trafficking of proteins to and from vacuoles. The vacuolar acidification is regulated by the PI3K-V-ATPase pathway in the methyl jasmonate-induced leaf senescence Arabidopsis thaliana