Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Liu, X.; Van Acker, R.; Voorend, W.; Pallidis, A.; Goeminne, G.; Pollier, J.; Morreel, K.; Kim, H.; Muylle, H.; Bosio, M.; Ralph, J.; Vanholme, R.; Boerjan, W.
    Rewired phenolic metabolism and improved saccharification efficiency of a Zea mays cinnamyl alcohol dehydrogenase 2 (zmcad2) mutant (2021), Plant J., 105, 1240-1257 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.195 4-coumaric aldehyde + NADPH + H+ Zea mays
-
 4-coumaric alcohol + NADP+
-
 ?
1.1.1.195 cinnamyl aldehyde + NADPH + H+ Zea mays
-
 cinnamyl alcohol + NADP+
-
 ?
1.1.1.195 coniferyl aldehyde + NADPH + H+ Zea mays
-
 coniferyl alcohol + NADP+ ? ?
1.1.1.195 sinapyl aldehyde + NADPH + H+ Zea mays
-
 sinapyl alcohol + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.195 Zea mays
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.195 4-coumaric aldehyde + NADPH + H+
-
 Zea mays 4-coumaric alcohol + NADP+
-
 ?
1.1.1.195 cinnamyl aldehyde + NADPH + H+
-
 Zea mays cinnamyl alcohol + NADP+
-
 ?
1.1.1.195 coniferyl aldehyde + NADPH + H+
-
 Zea mays coniferyl alcohol + NADP+ ? ?
1.1.1.195 sinapyl aldehyde + NADPH + H+
-
 Zea mays sinapyl alcohol + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.195 CAD2
-
 Zea mays
1.1.1.195 cinnamyl alcohol dehydrogenase 2
-
 Zea mays

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.195 NADPH
-
 Zea mays

General Information

EC Number General Information Comment Organism
1.1.1.195 malfunction isoform CAD2 downregulation improves saccharification efficiency. CAD2 enzyme-deficient mutants accumulate feruloyl and sinapoyl hexose conjugates. The total amount of lignin is reduced in the mutants, and only minor amounts of hydroxycinnamaldehydes are incorporated. Oligolignols composed of coniferyl and sinapyl alcohols are reduced, whereas those with one sinapaldehyde unit are increased in abundance in cad2 mutants Zea mays
1.1.1.195 physiological function the enzyme is involved in lignification Zea mays