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Literature summary extracted from

  • Munoz-Vargas, M.A.; Gonzalez-Gordo, S.; Palma, J.M.; Corpas, F.J.
    Inhibition of NADP-malic enzyme activity by H2S and NO in sweet pepper (Capsicum annuum L.) fruits (2020), Physiol. Plant., 168, 278-288 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.40 Diethylamine NONOate 35% inhibition at 5 mM Capsicum annuum
1.1.1.40 additional information peroxynitrite does not affect the enzyme even at a high concentration of 5 mM 3-morpholinosydnonimine Capsicum annuum
1.1.1.40 Na2S the enzyme activity is inhibited by up to 29-32% using 2 and 5 mM Na2S as H2S donor Capsicum annuum
1.1.1.40 S-nitrosocysteine 35% inhibition at 5 mM Capsicum annuum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.40 (S)-malate + NADP+ Capsicum annuum
-
 pyruvate + CO2 + NADPH + H+
-
 r
1.1.1.40 pyruvate + CO2 + NADPH + H+ Capsicum annuum
-
 (S)-malate + NADP+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.40 Capsicum annuum
-
 cultivar Melchor
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.40 fruit
-
 Capsicum annuum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.40 (S)-malate + NADP+
-
 Capsicum annuum pyruvate + CO2 + NADPH + H+
-
 r
1.1.1.40 pyruvate + CO2 + NADPH + H+
-
 Capsicum annuum (S)-malate + NADP+
-
 r

Synonyms

EC Number Synonyms Comment Organism
1.1.1.40 NADP-malic enzyme
-
 Capsicum annuum
1.1.1.40 NADP-ME
-
 Capsicum annuum

Expression

EC Number Organism Comment Expression
1.1.1.40 Capsicum annuum enzyme activity increases 1.5fold during fruit ripening up

General Information

EC Number General Information Comment Organism
1.1.1.40 physiological function the enzyme plays an important role in maintaining the supply of NADPH during pepper fruit ripening Capsicum annuum