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Literature summary extracted from

  • Anderson, S.E.; Sherman, E.X.; Weiss, D.S.; Rather, P.N.
    Aminoglycoside heteroresistance in Acinetobacter baumannii AB5075 (2018), mSphere, 3, e00271-18 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.46 nucleoside triphosphate + gentamicin Acinetobacter baumannii
-
 diphosphate + 2''-nucleotidylgentamicin
-
 ?
2.7.7.46 nucleoside triphosphate + gentamicin Acinetobacter baumannii AB5075
-
 diphosphate + 2''-nucleotidylgentamicin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.46 Acinetobacter baumannii B0VCJ4
-
-
2.7.7.46 Acinetobacter baumannii AB5075 B0VCJ4
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.46 ATP + gentamicin
-
 Acinetobacter baumannii diphosphate + 2''-adenylylgentamicin
-
 ?
2.7.7.46 ATP + gentamicin
-
 Acinetobacter baumannii AB5075 diphosphate + 2''-adenylylgentamicin
-
 ?
2.7.7.46 nucleoside triphosphate + gentamicin
-
 Acinetobacter baumannii diphosphate + 2''-nucleotidylgentamicin
-
 ?
2.7.7.46 nucleoside triphosphate + gentamicin
-
 Acinetobacter baumannii AB5075 diphosphate + 2''-nucleotidylgentamicin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.46 aadB
-
 Acinetobacter baumannii
2.7.7.46 aadB(ant2')Ia
-
 Acinetobacter baumannii
2.7.7.46 aminoglycoside adenylyltransferase
-
 Acinetobacter baumannii

Expression

EC Number Organism Comment Expression
2.7.7.46 Acinetobacter baumannii tobramycin-resistant subpopulations of Acinetobacter baumannii exhibit increased enzyme expression up