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Literature summary extracted from

  • Kamikubo, K.; Tsukamoto, O.; Uyama-Saito, Y.; Oya, R.; Tsubota, T.; Fujino, N.; Asano, Y.; Kato, H.; Matsuoka, K.; Takashima, S.
    Non-radioactive in vitro cardiac myosin light chain kinase assays (2020), J. Vis. Exp., 160, e61168 .
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.18 Calmodulin
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.11.18 0.005
-
 [ventricular isoform of myosin regulatory light chain MLC2v] at 25°C, pH not specified in the publication Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.18 Ca2+ required Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.18 ATP + [ventricular isoform of myosin regulatory light chain MLC2v] Homo sapiens
-
 ADP + [ventricular isoform of myosin regulatory light chain MLC2v] phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.18 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.18 heart
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.18 ATP + [ventricular isoform of myosin regulatory light chain MLC2v]
-
 Homo sapiens ADP + [ventricular isoform of myosin regulatory light chain MLC2v] phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.18 cardiac-specific myosin regulatory light chain kinase
-
 Homo sapiens
2.7.11.18 cMLCK
-
 Homo sapiens