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Literature summary extracted from

  • Kalbermatter, D.; Chiu, P.L.; Jeckelmann, J.M.; Ucurum, Z.; Walz, T.; Fotiadis, D.
    Electron crystallography reveals that substrate release from the PTS IIC glucose transporter is coupled to a subtle conformational change (2017), J. Struct. Biol., 199, 39-45 .
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.7.1.199
-
 Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.199 membrane integral membrane protein Escherichia coli 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.199 [protein]-Npi-phospho-L-histidine + D-glucose[side 1] Escherichia coli the enzyme is highly stereoselective for its substrate D-glucose [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.199 Escherichia coli P69783
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.199
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.199 additional information the enzyme does not bind L-glucose Escherichia coli ?
-
-
2.7.1.199 [protein]-Npi-phospho-L-histidine + D-glucose[side 1] the enzyme is highly stereoselective for its substrate D-glucose Escherichia coli [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.1.199 homodimer x-ray crystallography Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
2.7.1.199 glucose-specific EII complex
-
 Escherichia coli
2.7.1.199 IICB the glucose-specific phosphotransferase system includes the integral membrane protein IICB that couples the transmembrane transport of D-glucose to its phosphorylation Escherichia coli
2.7.1.199 IICglc glucose-specific IIC transport domain Escherichia coli
2.7.1.199 PTS IIC glucose transporter
-
 Escherichia coli