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Literature summary extracted from

  • Cassetta, A.; Stojan, J.; Krastanova, I.; Kristan, K.; Brunskole Svegelj, M.; Lamba, D.; Lanisnik Rizner, T.
    Structural basis for inhibition of 17beta-hydroxysteroid dehydrogenases by phytoestrogens The case of fungal 17beta-HSDcl (2017), J. Steroid Biochem. Mol. Biol., 171, 80-93 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.62 expressed as a glutathione S-transferase fusion protein in Escherichia coli BL21 cells Curvularia lunata

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.62
-
 Curvularia lunata

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.62 3,7-dihydroxyflavone
-
 Curvularia lunata
1.1.1.62 3-hydroxyflavone
-
 Curvularia lunata
1.1.1.62 Biochanin A
-
 Curvularia lunata
1.1.1.62 fisetin
-
 Curvularia lunata
1.1.1.62 genistein
-
 Curvularia lunata
1.1.1.62 isoflavones
-
 Curvularia lunata
1.1.1.62 kaempferol
-
 Curvularia lunata
1.1.1.62 luteolin
-
 Curvularia lunata
1.1.1.62 naringenin
-
 Curvularia lunata
1.1.1.62 quercetin
-
 Curvularia lunata

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.62 Curvularia lunata O93874
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.62
-
 Curvularia lunata

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.62 4-oestrene-17beta-ol-3-one + NADP+
-
 Curvularia lunata 4-oestrene-3,17-dione + NADPH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.62 17beta-HSDcl
-
 Curvularia lunata