Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Choi, K.; Heath, R.; Rock, C.
    beta-Ketoacyl-acyl carrier protein synthase III (FabH) is a determining factor in branched-chain fatty acid biosynthesis (2000), J. Bacteriol., 182, 365-370 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.180 Bacillus subtilis O07600 isoform FabH2, Cf. EC 2.3.1.300
-
2.3.1.180 Bacillus subtilis O34746 cf. EC 2.3.1.300
-
2.3.1.180 Bacillus subtilis 168 O07600 isoform FabH2, Cf. EC 2.3.1.300
-
2.3.1.180 Bacillus subtilis 168 O34746 cf. EC 2.3.1.300
-
2.3.1.300 Bacillus subtilis O07600 isoform FabH2, Cf. EC 2.3.1.180
-
2.3.1.300 Bacillus subtilis O34746
-
-
2.3.1.300 Bacillus subtilis 168 O07600 isoform FabH2, Cf. EC 2.3.1.180
-
2.3.1.300 Bacillus subtilis 168 O34746
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.180 0.016
-
 substrate isovaleryl-CoA, pH 7, 37°C Bacillus subtilis
2.3.1.180 0.058
-
 substrate isobutanoyl-CoA, pH 7, 37°C Bacillus subtilis
2.3.1.300 0.149
-
 substrate isobutanoyl-CoA, pH 7, 37°C Bacillus subtilis
2.3.1.300 0.155
-
 substrate 2-methylbutanoyl-CoA, pH 7, 37°C Bacillus subtilis
2.3.1.300 0.162
-
 substrate isovaleryl-CoA, pH 7, 37°C Bacillus subtilis
2.3.1.300 0.79
-
 substrate 2-methylbutanoyl-CoA, pH 7, 37°C Bacillus subtilis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.180 acetyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 3-oxobutanoyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 acetyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 168 3-oxobutanoyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 butanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2
-
 ?
2.3.1.180 butanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 168 3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2
-
 ?
2.3.1.180 heptanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 3-oxo-nonanoyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 heptanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 168 3-oxo-nonanoyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 hexanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 3-oxo-octanoyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 hexanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 168 3-oxo-octanoyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 octanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 octanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 168 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2
-
 ?
2.3.1.180 propanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 3-oxopentanoyl-[acyl-carrier-protein] + CoA + CO2
-
 ?
2.3.1.180 valeryl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 3-oxoheptanoyl-[acyl-carrier-protein] + CoA + CO2
-
 ?
2.3.1.300 2-methylbutanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 4-methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2
-
 ?
2.3.1.300 isobutanoyl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis 5-methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2
-
 ?
2.3.1.300 isovaleryl-CoA + malonyl-[acyl-carrier protein]
-
 Bacillus subtilis ? + CoA + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.180 ? x * 39800, SDS-PAGE, His-tagged recombinant protein Bacillus subtilis
2.3.1.180 ? x * 42700, SDS-PAGE, His-tagged recombinant protein Bacillus subtilis
2.3.1.300 ? x * 39800, SDS-PAGE, His-tagged recombinant protein Bacillus subtilis
2.3.1.300 ? x * 42700, SDS-PAGE, His-tagged recombinant protein Bacillus subtilis

Synonyms

EC Number Synonyms Comment Organism
2.3.1.180 FabH1
-
 Bacillus subtilis
2.3.1.180 FabH2
-
 Bacillus subtilis
2.3.1.180 FabHA
-
 Bacillus subtilis
2.3.1.180 FabHB
-
 Bacillus subtilis
2.3.1.300 FabH1
-
 Bacillus subtilis
2.3.1.300 FabH2
-
 Bacillus subtilis
2.3.1.300 FabHA
-
 Bacillus subtilis
2.3.1.300 FabHB
-
 Bacillus subtilis