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Literature summary extracted from
- A novel stage-specific glycosomal nucleoside diphosphate kinase from Trypanosoma cruzi (2017), Folia Parasitol., 64, 0006 .
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 2.7.4.6 | cloned and expressed in Escherichia coli | Trypanosoma cruzi |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 2.7.4.6 | 1.1 | - |
dTDP | pH and temperature not specified in the publication | Trypanosoma cruzi |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 2.7.4.6 | glycosome | - |
Trypanosoma cruzi | 20015 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 2.7.4.6 | 39300 | - |
calculated from sequence | Trypanosoma cruzi |
| 2.7.4.6 | 41800 | - |
SDS-PAGE | Trypanosoma cruzi |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.7.4.6 | Trypanosoma cruzi | Q4E256 | - |
- |
| 2.7.4.6 | Trypanosoma cruzi CL Brener | Q4E256 | - |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 2.7.4.6 | - |
Trypanosoma cruzi |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.7.4.6 | trypomastigote | the isoenzyme form TcNDPK3 is found only in the bloodstream trypomastigotes. TcNDPK3 mRNA is also detected at lower levels in amastigotes suggesting regulation at protein and mRNA level | Trypanosoma cruzi | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.7.4.6 | ATP + dTDP | - |
Trypanosoma cruzi | ADP + dTTP | - |
? | |
| 2.7.4.6 | ATP + dTDP | - |
Trypanosoma cruzi CL Brener | ADP + dTTP | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 2.7.4.6 | ? | x * 41800, SDS-PAGE | Trypanosoma cruzi |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 2.7.4.6 | TcNDPK3 | - |
Trypanosoma cruzi |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 2.7.4.6 | Trypanosoma cruzi | calculated from sequence | - |
5.2 |
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Release 2023.1 (January 2023)
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