EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.184 | daidzein | 71% residual activity at 0.05 mM | Homo sapiens | |
1.1.1.184 | daidzin | 74% residual activity at 0.05 mM | Homo sapiens | |
1.1.1.184 | genistein | 63% residual activity at 0.05 mM | Homo sapiens | |
1.1.1.184 | quercetin | - |
Homo sapiens | |
1.1.1.184 | quercitrin | - |
Homo sapiens | |
1.1.1.184 | rutin | - |
Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.184 | 0.0046 | - |
9,10-phenantrenequinone | at pH 8.4 and 37°C | Homo sapiens | |
1.1.1.184 | 0.0065 | - |
glutathionyl-nonanal | at pH 8.4 and 37°C | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.184 | Homo sapiens | P16152 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.184 | - |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.184 | 3-glutathionyl-4-hydroxynonanal + NADPH + H+ | - |
Homo sapiens | 3-glutathionyl-1,4-dihydroxynonane + NADP+ | - |
? | |
1.1.1.184 | 3-glutathionyl-4-hydroxynonanal hemiacetal + NADPH + H+ | - |
Homo sapiens | 3-glutathionyl-gamma-nonanolactone + NADP+ | - |
? | |
1.1.1.184 | 4-hydroxy-2-hexenal + NADPH + H+ | - |
Homo sapiens | ? | - |
? | |
1.1.1.184 | 9,10-phenantrenequinone + NADPH + H+ | - |
Homo sapiens | ? | - |
? | |
1.1.1.184 | glutathionyl-nonanal + NADPH + H+ | - |
Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.184 | carbonyl reductase 1 | - |
Homo sapiens |
1.1.1.184 | CBR1 | - |
Homo sapiens |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.184 | 30.8 | - |
glutathionyl-nonanal | at pH 8.4 and 37°C | Homo sapiens | |
1.1.1.184 | 66.7 | - |
9,10-phenantrenequinone | at pH 8.4 and 37°C | Homo sapiens |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.1.1.184 | 0.00074 | - |
at pH 8.4 and 37°C | Homo sapiens | rutin | |
1.1.1.184 | 0.00165 | - |
at pH 8.4 and 37°C | Homo sapiens | quercetin | |
1.1.1.184 | 0.00182 | - |
at pH 8.4 and 37°C | Homo sapiens | quercitrin |