EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.5.1.53 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.5.1.53 | liver | - |
Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.5.1.53 | 5,10-methylenetetrahydrofolate + NADPH + H+ | - |
Sus scrofa | 5-methyltetrahydrofolate + NADP+ | - |
? | |
1.5.1.53 | 5-methyltetrahydrofolate + oxidized menadione | - |
Sus scrofa | 5,10-methylenetetrahydrofolate + reduced menadione | - |
? | |
1.5.1.53 | NADPH + H+ + oxidized menadione | - |
Sus scrofa | NADP+ + reduced menadione | - |
? |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.5.1.53 | metabolism | methylenetetrahydrofolate reductase stereospecifically removes the pro-S hydrogen from the 4-position of NADPH. The oxidation of NADPH is largely or entirely rate limiting in the reductive half-reaction and in NADPH-menadione oxidoreductase turnover at saturating menadione concentration | Sus scrofa |