Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Zhu, X.; Su, M.; Manickam, K.; Zhang, W.
    Bacterial genome mining of enzymatic tools for alkyne biosynthesis (2015), ACS Chem. Biol., 10, 2785-2793 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.78 dec-9-enoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+ Teredinibacter turnerae
-
 dec-9-ynoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
-
 ?
1.14.19.78 dec-9-enoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+ Teredinibacter turnerae T7901
-
 dec-9-ynoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
-
 ?
1.14.19.78 decanoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+ Teredinibacter turnerae
-
 dec-9-enoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
-
 ?
1.14.19.78 decanoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+ Teredinibacter turnerae T7901
-
 dec-9-enoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
-
 ?
1.14.19.78 decanoyl-[acyl-carrier protein] + 4 reduced ferredoxin [iron-sulfur] cluster + 2 O2 + 4 H+ Teredinibacter turnerae enzyme is specific for decanoyl-[acyl-carrier protein] dec-9-ynoyl-[acyl-carrier protein] + 4 oxidized ferredoxin [iron-sulfur] cluster + 4 H2O
-
 ?
1.14.19.78 decanoyl-[acyl-carrier protein] + 4 reduced ferredoxin [iron-sulfur] cluster + 2 O2 + 4 H+ Teredinibacter turnerae T7901 enzyme is specific for decanoyl-[acyl-carrier protein] dec-9-ynoyl-[acyl-carrier protein] + 4 oxidized ferredoxin [iron-sulfur] cluster + 4 H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.78 Teredinibacter turnerae
-
-
-
1.14.19.78 Teredinibacter turnerae T7901
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.78 dec-9-enoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+
-
 Teredinibacter turnerae dec-9-ynoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
-
 ?
1.14.19.78 dec-9-enoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+
-
 Teredinibacter turnerae T7901 dec-9-ynoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
-
 ?
1.14.19.78 decanoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+
-
 Teredinibacter turnerae dec-9-enoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
-
 ?
1.14.19.78 decanoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+
-
 Teredinibacter turnerae T7901 dec-9-enoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O
-
 ?
1.14.19.78 decanoyl-[acyl-carrier protein] + 4 reduced ferredoxin [iron-sulfur] cluster + 2 O2 + 4 H+ enzyme is specific for decanoyl-[acyl-carrier protein] Teredinibacter turnerae dec-9-ynoyl-[acyl-carrier protein] + 4 oxidized ferredoxin [iron-sulfur] cluster + 4 H2O
-
 ?
1.14.19.78 decanoyl-[acyl-carrier protein] + 4 reduced ferredoxin [iron-sulfur] cluster + 2 O2 + 4 H+ enzyme is specific for decanoyl-[acyl-carrier protein] Teredinibacter turnerae T7901 dec-9-ynoyl-[acyl-carrier protein] + 4 oxidized ferredoxin [iron-sulfur] cluster + 4 H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.78 ttuB
-
 Teredinibacter turnerae

General Information

EC Number General Information Comment Organism
1.14.19.78 physiological function enzyme is part of a terminal alkyne biosynthetic pathway comprised of TtuA, -B, and -C. TtuB is a bifunctional desaturase/acetylenase that efficiently catalyzes two sequential O2-dependent dehydrogenation reactions. TtuB is essential for the production of both the terminal alkene and alkyne functionalities. Activity is maximal when decanoate is loaded onto a dedicated acyl-carrier protein, i.e. TtuC Teredinibacter turnerae