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Literature summary extracted from

  • Hassinen, A.; Khoder-Agha, F.; Khosrowabadi, E.; Mennerich, D.; Harrus, D.; Noel, M.; Dimova, E.Y.; Glumoff, T.; Harduin-Lepers, A.; Kietzmann, T.; Kellokumpu, S.
    A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I (2019), Redox Biol., 24, 101182 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.3.1 expressed in COS-7 cells Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
2.4.3.1 C353A/C406A enzymatically inactive Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.3.1 additional information the enzyme is inactivated by hypoxia Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.3.1 Golgi apparatus
-
 Homo sapiens 5794
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.1 Homo sapiens P15907
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.1 CMP-N-acetyl-beta-neuraminate + desialylated fetuin
-
 Homo sapiens CMP + ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.3.1 ? x * 45000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.4.3.1 alpha-2,6-sialyltransferase
-
 Homo sapiens
2.4.3.1 ST6Gal-I
-
 Homo sapiens