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Literature summary extracted from
- Sequestration and microsomal C-25 hydroxylation of [3H]-vitamin D3 by the rat liver (1985), Metabolism, 34, 244-250 .
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.17.99.10 | 0.0000145 | - |
vitamin D3 | pH 7.5, 37°C | Rattus norvegicus |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.17.99.10 | endoplasmic reticulum | - |
Rattus norvegicus | 5783 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.17.99.10 | vitamin D3 + acceptor + H2O | Rattus norvegicus | - |
25-hydroxy-vitamin D3 + reduced acceptor | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.17.99.10 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.17.99.10 | hepatocyte | - |
Rattus norvegicus | - |
| 1.17.99.10 | liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.17.99.10 | vitamin D3 + acceptor + H2O | - |
Rattus norvegicus | 25-hydroxy-vitamin D3 + reduced acceptor | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.17.99.10 | D3 25-hydroxylase | - |
Rattus norvegicus |
| 1.17.99.10 | vitamin D3 25-hydroxylase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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