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Literature summary extracted from

  • Fotschki, J.; Wroblewska, B.; Fotschki, B.; Kalicki, B.; Rigby, N.; Mackie, A.
    Microbial transglutaminase alters the immunogenic potential and cross-reactivity of horse and cow milk proteins (2020), J. Dairy Sci., 103, 2153-2166 .
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.2.13 additional information microbial transglutaminase alters the immunogenic potential and cross-reactivity of horse and cow milk proteins. Possibility of reducing the immunoreactivity of horse milk proteins by microbial transglutaminase (TG) polymerization. The diet based on modified horse milk proteins could be an alternative for some patients with cow milk protein allergy Streptomyces mobaraensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.2.13 alpha-casein glutamine + alkylamine Streptomyces mobaraensis
-
 alpha-casein N5-alkylglutamine + NH3
-
 ?
2.3.2.13 protein glutamine + alkylamine Streptomyces mobaraensis
-
 protein N5-alkylglutamine + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Streptomyces mobaraensis P81453
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 alpha-casein glutamine + alkylamine
-
 Streptomyces mobaraensis alpha-casein N5-alkylglutamine + NH3
-
 ?
2.3.2.13 additional information crosslinking activity and IgG reactivity after digestion with cow and horse milk proteins, detailed overview Streptomyces mobaraensis ?
-
-
2.3.2.13 protein glutamine + alkylamine
-
 Streptomyces mobaraensis protein N5-alkylglutamine + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.2.13 microbial transglutaminase
-
 Streptomyces mobaraensis

General Information

EC Number General Information Comment Organism
2.3.2.13 physiological function microbial transglutaminase alters the immunogenic potential and cross-reactivity of horse and cow milk proteins. The effect of TG on immunoreactivity depends on enzyme quantity and milk protein type. Determination of immunoreactivity of milk proteins by competitive ELISA Streptomyces mobaraensis