EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.149 | ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate | Drosophila melanogaster | - |
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.149 | Drosophila melanogaster | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.149 | larva | - |
Drosophila melanogaster | - |
2.7.1.149 | pupa | - |
Drosophila melanogaster | - |
2.7.1.149 | retina | - |
Drosophila melanogaster | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.149 | ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate | - |
Drosophila melanogaster | ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.149 | phosphatidylinositol 5 phosphate 4-kinase | - |
Drosophila melanogaster |
2.7.1.149 | PIP4K | - |
Drosophila melanogaster |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.7.1.149 | malfunction | flies lacking the enzyme show mislocalization of rhodopsin 1 on expanded endomembranes within the cell body. Enzyme loss is associated with increased clathrin-mediated endocytosis and an enlarged Rab5-positive compartment in cultured Drosophila cells | Drosophila melanogaster |
2.7.1.149 | physiological function | the enzyme regulates clathrin-mediated endocytosis of rhodopsin 1 and supports rhodopsin 1 trafficking during pupal metamorphosis | Drosophila melanogaster |