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Literature summary extracted from

  • Khurana, S.; Coffey, M.J.; John, A.; Uboldi, A.D.; Huynh, M.H.; Stewart, R.J.; Carruthers, V.B.; Tonkin, C.J.; Goddard-Borger, E.D.; Scott, N.E.
    Protein O-fucosyltransferase 2-mediated O-glycosylation of the adhesin MIC2 is dispensable for Toxoplasma gondii tachyzoite infection (2019), J. Biol. Chem., 294, 1541-1553 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.221 GDP-L-fucose + micronemal protein 2 Toxoplasma gondii
-
 GDP + fucosylated micronemal protein 2
-
 ?
2.4.1.221 GDP-L-fucose + micronemal protein 2 Toxoplasma gondii ATCC 50853
-
 GDP + fucosylated micronemal protein 2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.221 Toxoplasma gondii S7WCF5
-
-
2.4.1.221 Toxoplasma gondii ATCC 50853 S7WCF5
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.221 GDP-L-fucose + micronemal protein 2
-
 Toxoplasma gondii GDP + fucosylated micronemal protein 2
-
 ?
2.4.1.221 GDP-L-fucose + micronemal protein 2
-
 Toxoplasma gondii ATCC 50853 GDP + fucosylated micronemal protein 2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.221 FUT2
-
 Toxoplasma gondii
2.4.1.221 protein O-fucosyltransferase 2
-
 Toxoplasma gondii
2.4.1.221 TGGT1_273550
-
 Toxoplasma gondii

General Information

EC Number General Information Comment Organism
2.4.1.221 physiological function the enzyme O-glycosylates micronemal protein 2 (MIC2). This glycan is dispensable in Toxoplasma gondii tachyzoites and for Toxoplasma gondii infectivity Toxoplasma gondii