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Literature summary extracted from

  • Boland, C.; Hayes, P.; Santa-Maria, I.; Nishimura, S.; Kelly, V.
    Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase (2009), J. Biol. Chem., 284, 18218-18227 .
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.2.64 mitochondrion
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 Mus musculus 5739
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.64 guanine34 in tRNA + queuine Mus musculus the enzyme is responsible for the formation of queuosine in the anticodon loop (position 34) of tRNAAsp, tRNAAsn, tRNAHis, and tRNATyr queuine34 in tRNA + guanine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.64 Mus musculus Q9JMA2 AND B8ZXI1 Q9JMA2: catalytic subunit 1 (QTRT1), B8ZXI1: accessory subunit 2 (QTRT2)
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.64 guanine34 in tRNA + queuine the enzyme is responsible for the formation of queuosine in the anticodon loop (position 34) of tRNAAsp, tRNAAsn, tRNAHis, and tRNATyr Mus musculus queuine34 in tRNA + guanine
-
 ?
2.4.2.64 guanine34 in tRNA + queuine formation of queuosine in the anticodon loop (position 34) of tRNAAsp, tRNAAsn, tRNAHis, and tRNATyr Mus musculus queuine34 in tRNA + guanine
-
 ?

General Information

EC Number General Information Comment Organism
2.4.2.64 metabolism the enzyme is responsible for the formation of queuosine in the anticodon loop (position 34) of tRNAAsp, tRNAAsn, tRNAHis, and tRNATyr Mus musculus