Literature summary extracted from

Ziamajidi, N.; Jamshidi, S.; Ehsani-Zonouz, A.
In-silico and in-vitro investigation on the phenylalanine metabolites' interactions with hexokinase of Rat's brain mitochondria (2017), J. Bioenerg. Biomembr., 49, 139-147 .

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.1.1	phenylpyruvic acid	the enzyme decreases the activity of enzyme in the presence and absence of glucose-6-phosphate (G6P) and increases the release of the enzyme from mitochondria	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.7.1.1	mitochondrion	-	Rattus norvegicus	5739	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.1	Rattus norvegicus	P05708	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.1	brain	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.1	ATP + D-glucose	-	Rattus norvegicus	ADP + D-glucose 6-phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.1.1	HK-I	-	Rattus norvegicus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)