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Literature summary extracted from

  • Song, Q.; Meng, X.; Liao, Y.; Zhang, W.; Ye, J.; Xu, F.
    Transcriptome-guided gene isolation, characterization and expression analysis of a phosphomevalonate kinase gene (GbPMK) from Ginkgo biloba (2018), Int. J. Agric. Biol., 20, 1080-1088 .
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.4.2 gene GbPMK, DNA and amino acid sequence determination and analysis, phylogenetic analysis, quantitative RT-PCR enzyme expression analysis, subcloning and recombinant expression in Escherichia coli strain DH5alpha Ginkgo biloba

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.2 ATP + (R)-5-phosphomevalonate Ginkgo biloba
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ADP + (R)-5-diphosphomevalonate
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?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.2 Ginkgo biloba A0A346QPQ2 collected from Ginkgo Botanical Garden of Yangtze University, Jingzhou, Hubei province, China
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.2 cone female and male Ginkgo biloba
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2.7.4.2 fruit
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Ginkgo biloba
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2.7.4.2 leaf
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Ginkgo biloba
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2.7.4.2 additional information analysis of expression profile of GbPMK in different tissues. GbPMK exhibits tissue-specific expression, with the highest expression in leaves and the lowest expression in male strobili Ginkgo biloba
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2.7.4.2 root
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Ginkgo biloba
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2.7.4.2 stem
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Ginkgo biloba
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.2 ATP + (R)-5-phosphomevalonate
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Ginkgo biloba ADP + (R)-5-diphosphomevalonate
-
?

Subunits

EC Number Subunits Comment Organism
2.7.4.2 ? x * 55960, sequence calculation Ginkgo biloba

Synonyms

EC Number Synonyms Comment Organism
2.7.4.2 GbPMK
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Ginkgo biloba
2.7.4.2 PMK
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Ginkgo biloba

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.7.4.2 Ginkgo biloba sequence calculation
-
5.74

Expression

EC Number Organism Comment Expression
2.7.4.2 Ginkgo biloba Under methyljasmonate treatment, the expression level of GbPMK significantly decreases in different degrees with prolonged treated time. After 1 d, the expression level of GbPMK is reduced by 0.45fold compared to control down
2.7.4.2 Ginkgo biloba salicylate generally increases the expression level of GbPMK. The expression first increases, then decreases, and finally reaches the highest level 2 d after the treatment. The expression level is 1.21fold higher than that in the control 2 d after treatments. The expression levels in abscisic acid and ethylene treatments are 3.03 and 1.56fold higher compared to control. After 4 d of treatment, the expression levels decrease to varying degrees up

General Information

EC Number General Information Comment Organism
2.7.4.2 evolution phosphomethoxylate kinase (PMK) is a member of the GHMP kinase superfamily. The GbPMK protein has four conserved domains and one conserved region of the GHMP kinase family. GbPMK possesses a conserved sequence structure and sequence characteristics. PMK phylogenetic and molecular evolution analyses Ginkgo biloba
2.7.4.2 physiological function phosphomethoxylate kinase (PMK) is one of the core enzyme in the mevalonate pathway, one of the two pathways in plants that can synthase terpenoids. Terpenoids are main active ingredients of Ginkgo biloba Ginkgo biloba