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Literature summary extracted from

  • Wyckelsma, V.L.; Lindkvist, W.; Venckunas, T.; Brazaitis, M.; Kamandulis, S.; Paeaesuke, M.; Ereline, J.; Westerblad, H.; Andersson, D.C.
    Kynurenine aminotransferase isoforms display fiber-type specific expression in young and old human skeletal muscle (2020), Exp. Gerontol., 134, 110880 .
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.6.1.7 mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.7 L-kynurenine + 2-oxoglutarate Homo sapiens
-
 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.7 Homo sapiens
-
-
-
2.6.1.7 Homo sapiens Q6YP21
-
-
2.6.1.7 Homo sapiens Q8N5Z0
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.7 skeletal muscle the enzyme is generally more expressed in oxidative muscle fibers Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.7 L-kynurenine + 2-oxoglutarate
-
 Homo sapiens 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.6.1.7 KAT I isoform Homo sapiens
2.6.1.7 KAT III isoform Homo sapiens
2.6.1.7 KAT IV isoform Homo sapiens
2.6.1.7 kynurenine aminotransferase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.7 pyridoxal 5'-phosphate
-
 Homo sapiens