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Literature summary extracted from

  • Wang, J.; Xu, S.; Lv, W.; Shi, F.; Mei, S.; Shan, A.; Xu, J.; Yang, Y.
    Uridine phosphorylase 1 is a novel immune-related target and predicts worse survival in brain glioma (2020), Cancer Med., 9, 5940-5947 .
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.4.2.3 diagnostics UPP1 may serve as a negative prognosticator in glioma, analysis of the prognostic value of UPP1 for glioma, overview. UPP1 predicts shorter survival for glioma Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.3 uracil + alpha-D-ribose 1-phosphate Homo sapiens
-
 uridine + phosphate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.3 Homo sapiens Q16831
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.3 glioblastoma cell UPP1 is significantly upregulated in glioma, especially in glioblastoma Homo sapiens
-
2.4.2.3 glioma cell UPP1 is significantly upregulated in glioma, especially in glioblastoma Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.3 uracil + alpha-D-ribose 1-phosphate
-
 Homo sapiens uridine + phosphate
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.4.2.3 UPP1
-
 Homo sapiens
2.4.2.3 uridine phosphorylase 1
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
2.4.2.3 Homo sapiens UPP1 is significantly upregulated in glioma, especially in glioblastoma up

General Information

EC Number General Information Comment Organism
2.4.2.3 physiological function UPP1 interacts with immune checkpoint members in glioma Homo sapiens