EC Number | Cloned (Comment) | Organism |
---|---|---|
2.5.1.18 | expressed in Escherichia coli BL21 cells | Callithrix jacchus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.5.1.18 | 0.009 | - |
1-iodohexane | isoform GSTM5, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.009 | - |
1-iodohexane | isoform GSTT1, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.021 | - |
1-iodohexane | isoform GSTM4, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.022 | - |
1-iodohexane | isoform GSTM2, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.026 | - |
1-iodohexane | isoform GSTM3, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.064 | - |
styrene 7,8-oxide | isoform GSTM2, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.09 | - |
styrene 7,8-oxide | isoform GSTM5, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.11 | - |
styrene 7,8-oxide | isoform GSTM3, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.16 | - |
styrene 7,8-oxide | isoform GSTT1, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.183 | - |
styrene 7,8-oxide | isoform GSTT4, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.365 | - |
styrene 7,8-oxide | isoform GSTM4, at pH 7.4 and 25°C | Callithrix jacchus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.5.1.18 | cytosol | - |
Callithrix jacchus | 5829 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.18 | Callithrix jacchus | - |
common marmoset | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.5.1.18 | brain | isoform GSTA4 mRNA is expressed most abundantly in brain | Callithrix jacchus | - |
2.5.1.18 | kidney | isoform GSTO2 mRNA is expressed most abundantly in kidney | Callithrix jacchus | - |
2.5.1.18 | liver | isoforms GSTA1, GSTA3, GSTA4L, GSTK1, GSTT1, GSTZ1, and MGST1 mRNAs are expressed most abundantly in liver | Callithrix jacchus | - |
2.5.1.18 | lung | isoforms GSTM4, GSTO1, and GSTP1 mRNAs are expressed most abundantly in lung | Callithrix jacchus | - |
2.5.1.18 | small intestine | isoforms GSTM2, GSTM3, GSTM5, GSTS1, MGST2, and MGST3 mRNAs are expressed most abundantly in small intestine | Callithrix jacchus | - |
2.5.1.18 | testis | expression of isoform GSTT4 and GSTT4L mRNAs is detected only in testis | Callithrix jacchus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.18 | glutathione + 1,2-epoxy-3-(4-nitrophenoxy)propane | - |
Callithrix jacchus | ? | - |
? | |
2.5.1.18 | glutathione + 1-chloro-2,4-dinitrobenzene | - |
Callithrix jacchus | chloride + 2,4-dinitrophenyl-glutathione | - |
? | |
2.5.1.18 | glutathione + 1-iodohexane | highest affinity substrate for isoforms GSTT1 and GSTM5 | Callithrix jacchus | iodide + hexyl-glutathione | - |
? | |
2.5.1.18 | glutathione + styrene 7,8-oxide | highest affinity substrate for isoforms GSTM2 and GSTM5 | Callithrix jacchus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.5.1.18 | glutathione S-transferase | - |
Callithrix jacchus |
2.5.1.18 | GST | - |
Callithrix jacchus |
2.5.1.18 | GSTA1 | isoform | Callithrix jacchus |
2.5.1.18 | GSTA3 | isoform | Callithrix jacchus |
2.5.1.18 | GSTA4 | isoform | Callithrix jacchus |
2.5.1.18 | GSTA4L | isoform | Callithrix jacchus |
2.5.1.18 | GSTK1 | isoform | Callithrix jacchus |
2.5.1.18 | GSTM2 | isoform | Callithrix jacchus |
2.5.1.18 | GSTM3 | isoform | Callithrix jacchus |
2.5.1.18 | GSTM4 | isoform | Callithrix jacchus |
2.5.1.18 | GSTM5 | isoform | Callithrix jacchus |
2.5.1.18 | GSTO1 | isoform | Callithrix jacchus |
2.5.1.18 | GSTO2 | isoform | Callithrix jacchus |
2.5.1.18 | GSTP1 | isoform | Callithrix jacchus |
2.5.1.18 | GSTT1 | isoform | Callithrix jacchus |
2.5.1.18 | GSTT4 | isoform | Callithrix jacchus |
2.5.1.18 | GSTT4L | isoform | Callithrix jacchus |
2.5.1.18 | Gstz1 | isoform | Callithrix jacchus |
2.5.1.18 | MGST1 | isoform | Callithrix jacchus |
2.5.1.18 | MGST2 | isoform | Callithrix jacchus |
2.5.1.18 | MGST3 | isoform | Callithrix jacchus |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.5.1.18 | 0.5 | - |
1-iodohexane | isoform GSTM2, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.55 | - |
1-iodohexane | isoform GSTM4, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.62 | - |
1-iodohexane | isoform GSTM3, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 0.8 | - |
1-iodohexane | isoform GSTM5, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 1.1 | - |
1-iodohexane | isoform GSTT1, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 1.78 | - |
styrene 7,8-oxide | isoform GSTT4, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 2.22 | - |
styrene 7,8-oxide | isoform GSTT1, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 2.4 | - |
styrene 7,8-oxide | isoform GSTM2, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 2.4 | - |
styrene 7,8-oxide | isoform GSTM3, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 3.13 | - |
styrene 7,8-oxide | isoform GSTM4, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 4.12 | - |
styrene 7,8-oxide | isoform GSTM5, at pH 7.4 and 25°C | Callithrix jacchus |
EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.5.1.18 | 8.3 | - |
styrene 7,8-oxide | isoform GSTM4, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 10 | - |
styrene 7,8-oxide | isoform GSTT4, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 13.3 | - |
styrene 7,8-oxide | isoform GSTT1, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 21.7 | - |
styrene 7,8-oxide | isoform GSTM3, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 23.3 | - |
1-iodohexane | isoform GSTM2, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 23.3 | - |
1-iodohexane | isoform GSTM3, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 26.7 | - |
1-iodohexane | isoform GSTM4, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 36.7 | - |
styrene 7,8-oxide | isoform GSTM2, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 45 | - |
styrene 7,8-oxide | isoform GSTM5, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 88.3 | - |
1-iodohexane | isoform GSTM5, at pH 7.4 and 25°C | Callithrix jacchus | |
2.5.1.18 | 121.7 | - |
1-iodohexane | isoform GSTT1, at pH 7.4 and 25°C | Callithrix jacchus |