Literature summary extracted from

Nyiri, K.; Mertens, H.D.T.; Tihanyi, B.; Nagy, G.N.; Kohegyi, B.; Matejka, J.; Harris, M.J.; Szabo, J.E.; Papp-Kadar, V.; Nemeth-Pongracz, V.; Ozohanics, O.; Vekey, K.; Svergun, D.I.; Borysik, A.J.; Vertessy, B.G.
Structural model of human dUTPase in complex with a novel proteinaceous inhibitor (2018), Sci. Rep., 8, 4326 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.6.1.23	expressed in Escherichia coli BL21(DE3) Rosetta cells	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.6.1.23	staphylococcal repressor protein StlSaPIBov1	highly potent inhibitor	Homo sapiens

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
3.6.1.23	54100	-	calculated from amino acid sequence	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.6.1.23	dUTP + H2O	Homo sapiens	-	dUMP + diphosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.6.1.23	Homo sapiens	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.6.1.23	-	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.6.1.23	dUTP + H2O	-	Homo sapiens	dUMP + diphosphate	-	?

Subunits

EC Number	Subunits	Comment	Organism
3.6.1.23	trimer	-	Homo sapiens

Synonyms

EC Number	Synonyms	Comment	Organism
3.6.1.23	deoxyuridine 5'-triphosphate nucleotidohydrolase	-	Homo sapiens
3.6.1.23	DUT	-	Homo sapiens
3.6.1.23	dUTPase	-	Homo sapiens

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
3.6.1.23	0.0000067	-	staphylococcal repressor protein StlSaPIBov1	at pH 7.5 and 20°C	Homo sapiens

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Release 2023.1 (January 2023)