EC Number | Cloned (Comment) | Organism |
---|---|---|
3.5.4.10 | overexpressed in Rosetta2 (DE3) cells | Thermococcus kodakarensis |
3.5.4.10 | overexpressed in Rosetta2 (DE3) cells | Archaeoglobus fulgidus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.4.10 | 0.00156 | - |
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | pH 7.3, 50°C | Thermococcus kodakarensis | |
3.5.4.10 | 0.0078 | - |
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | pH 7.3, 50°C | Archaeoglobus fulgidus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | Thermococcus kodakarensis | the enzyme catalyze the final step of de novo purine biosynthesis | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | Archaeoglobus fulgidus | the enzyme catalyze the final step of de novo purine biosynthesis | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | Archaeoglobus fulgidus ATCC 49558 | the enzyme catalyze the final step of de novo purine biosynthesis | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | Thermococcus kodakarensis ATCC BAA-918 | the enzyme catalyze the final step of de novo purine biosynthesis | IMP + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.4.10 | Archaeoglobus fulgidus | O28464 | - |
- |
3.5.4.10 | Archaeoglobus fulgidus ATCC 49558 | O28464 | - |
- |
3.5.4.10 | Thermococcus kodakarensis | Q5JD29 | - |
- |
3.5.4.10 | Thermococcus kodakarensis ATCC BAA-918 | Q5JD29 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.5.4.10 | - |
Thermococcus kodakarensis |
3.5.4.10 | - |
Archaeoglobus fulgidus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | - |
Thermococcus kodakarensis | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | - |
Archaeoglobus fulgidus | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | the enzyme catalyze the final step of de novo purine biosynthesis | Thermococcus kodakarensis | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | the enzyme catalyze the final step of de novo purine biosynthesis | Archaeoglobus fulgidus | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | - |
Archaeoglobus fulgidus ATCC 49558 | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | the enzyme catalyze the final step of de novo purine biosynthesis | Archaeoglobus fulgidus ATCC 49558 | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | - |
Thermococcus kodakarensis ATCC BAA-918 | IMP + H2O | - |
? | |
3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | the enzyme catalyze the final step of de novo purine biosynthesis | Thermococcus kodakarensis ATCC BAA-918 | IMP + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.5.4.10 | AF1811 | locus name | Archaeoglobus fulgidus |
3.5.4.10 | PurH2 | - |
Archaeoglobus fulgidus |
3.5.4.10 | PurH2-type IMP cyclohydrolase | - |
Archaeoglobus fulgidus |
3.5.4.10 | PurO | - |
Thermococcus kodakarensis |
3.5.4.10 | PurO-type IMP cyclohydrolase | - |
Thermococcus kodakarensis |
3.5.4.10 | TK0430 | - |
Thermococcus kodakarensis |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.5.4.10 | 60 | - |
- |
Archaeoglobus fulgidus |
3.5.4.10 | 70 | - |
- |
Thermococcus kodakarensis |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.4.10 | 0.48 | - |
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | pH 7.3, 50°C | Thermococcus kodakarensis | |
3.5.4.10 | 1.32 | - |
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | pH 7.3, 50°C | Archaeoglobus fulgidus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.5.4.10 | metabolism | the enzyme catalyze the final step of de novo purine biosynthesis | Thermococcus kodakarensis |
3.5.4.10 | metabolism | the enzyme catalyze the final step of de novo purine biosynthesis | Archaeoglobus fulgidus |
EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.4.10 | 307.7 | - |
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | pH 7.3, 50°C | Archaeoglobus fulgidus |