EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.7.1.2 | 4-fumarylacetoacetate + H2O | Arabidopsis thaliana | final step in the Tyr degradation pathway | acetoacetate + fumarate | - |
? | |
3.7.1.2 | 4-fumarylacetoacetate + H2O | Arabidopsis thaliana Col-0 | final step in the Tyr degradation pathway | acetoacetate + fumarate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.7.1.2 | Arabidopsis thaliana | Q8RW90 | - |
- |
3.7.1.2 | Arabidopsis thaliana Col-0 | Q8RW90 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.7.1.2 | 4-fumarylacetoacetate + H2O | - |
Arabidopsis thaliana | acetoacetate + fumarate | - |
? | |
3.7.1.2 | 4-fumarylacetoacetate + H2O | final step in the Tyr degradation pathway | Arabidopsis thaliana | acetoacetate + fumarate | - |
? | |
3.7.1.2 | 4-fumarylacetoacetate + H2O | - |
Arabidopsis thaliana Col-0 | acetoacetate + fumarate | - |
? | |
3.7.1.2 | 4-fumarylacetoacetate + H2O | final step in the Tyr degradation pathway | Arabidopsis thaliana Col-0 | acetoacetate + fumarate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.7.1.2 | fumarylacetoacetate hydrolase | - |
Arabidopsis thaliana |
3.7.1.2 | SSCD1 | - |
Arabidopsis thaliana |
EC Number | Organism | Comment | Expression |
---|---|---|---|
3.7.1.2 | Arabidopsis thaliana | the SSCD1 gene is up-regulated by salt stress and by H2O2 | up |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.7.1.2 | malfunction | the sscd1 mutant is hypersensitive to salt stress. The sscd1 mutant shows more accumulation of reactive oxygen species (ROS) and less up-regulation of some ROS-scavenging genes such as ASCORBATE PEROXIDASE 2 and COPPER/ZINC SUPEROXIDE DISMUTASE 1 compared with wild type under salt stress. The sscd1 mutant exhibits hypersensitivity to oxidative stress compared with wild type enzyme. Loss of fumarylacetoacetate hydrolase in sscd1 mutant leads to the accumulation of Tyr degradation intermediates, which impairs the up-regulation of some ROS-scavenging genes under salt stress, causing more accumulation of ROS, resulting in the hypersensitivity of sscd1 to salt stress | Arabidopsis thaliana |
3.7.1.2 | physiological function | final step in the Tyr degradation pathway | Arabidopsis thaliana |