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Literature summary extracted from

  • Lescano, C.I.; Martini, C.; Gonzalez, C.A.; Desimone, M.
    Allantoin accumulation mediated by allantoinase downregulation and transport by ureide permease 5 confers salt stress tolerance to Arabidopsis plants (2016), Plant Mol. Biol., 91, 581-595 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.2.5 gene ALN, semi-quantitative RT-PCR enzyme expression analysis Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
3.5.2.5 additional information generation of knockout by T-DNA insertion, knockdown, and stress-inducible mutants for AtALN revealing that allantoin accumulation is essential for salt stress tolerance, phenotypes, overview Arabidopsis thaliana

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.2.5 Zn2+ required Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.2.5 (S)-allantoin + H2O Arabidopsis thaliana
-
 allantoate
-
 ?
3.5.2.5 (S)-allantoin + H2O Arabidopsis thaliana Col-0
-
 allantoate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.2.5 Arabidopsis thaliana Q94AP0
-
-
3.5.2.5 Arabidopsis thaliana Col-0 Q94AP0
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.2.5 additional information the AtALN promoter activity is present in specific plant tissues during plant development and is strongly repressed by salt stress Arabidopsis thaliana
-
3.5.2.5 root
-
 Arabidopsis thaliana
-
3.5.2.5 seedling
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.2.5 (S)-allantoin + H2O
-
 Arabidopsis thaliana allantoate
-
 ?
3.5.2.5 (S)-allantoin + H2O
-
 Arabidopsis thaliana Col-0 allantoate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.2.5 ALN
-
 Arabidopsis thaliana
3.5.2.5 aln-1
-
 Arabidopsis thaliana
3.5.2.5 aln-2
-
 Arabidopsis thaliana
3.5.2.5 Salk_142607
-
 Arabidopsis thaliana
3.5.2.5 Salk_146783
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
3.5.2.5 Arabidopsis thaliana allantoin accumulation is mediated by allantoinase downregulation. The AtALN promoter activity is present in specific plant tissues during plant development and is strongly repressed by salt stress down

General Information

EC Number General Information Comment Organism
3.5.2.5 malfunction allantoin accumulation is mediated by allantoinase downregulation. Knockout, knockdown, and stress-inducible mutants of AtALN reveal that allantoin accumulation is essential for salt stress tolerance, phenotypes, overview Arabidopsis thaliana
3.5.2.5 metabolism expression of genes for allantoin synthesis and degradation are oppositely regulated during salt stress. The AtALN promoter activity is present in specific plant tissues during plant development and is strongly repressed by salt stress. Allantoin transport mediated by ureide permease 5 (AtUPS5) is an important event in salt stress alleviation Arabidopsis thaliana
3.5.2.5 physiological function allantoin accumulation is essential for salt stress tolerance. The regulation of the enzyme-encoding gene is mainly responsible for allantoin accumulation observed under salt stress. Possible roles of allantoin as a protectant compound in oxidative events or signaling, overview Arabidopsis thaliana