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Literature summary extracted from

  • Ponniah, S.; Shang, Z.; Akbudak, M.; Srivastava, V.; Manoharan, M.
    Down-regulation of hydroxycinnamoyl CoA shikimate hydroxycinnamoyl transferase, cinnamoyl CoA reductase, and cinnamyl alcohol dehydrogenase leads to lignin reduction in rice (Oryza sativa L. ssp. japonica cv. Nipponbare) (2017), Plant Biotechnol. Rep., 11, 17-27 .
No PubMed abstract available

Application

EC Number Application Comment Organism
2.3.1.133 agriculture downregulation of key genes involved in lignin biosynthesis, such as hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl transferase (HCT), cinnamoyl-CoA reductase (CCR), and cinnamyl alcohol dehydrogenase (CAD), through terminator-less constructs to reduce lignin content. T1 transgenic rice plants show 36-86% transcript reduction in HCT lines. Down-regulated lines show significant reduction in total lignin content with lignin reduction ranging from 4.6 to 10.8% Oryza sativa Japonica Group

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.44 Oryza sativa Japonica Group Q6K9A2 cultivar Nipponbare
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2.3.1.133 Oryza sativa Japonica Group
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Synonyms

EC Number Synonyms Comment Organism
1.2.1.44 CCR12 isoform Oryza sativa Japonica Group
1.2.1.44 CCR3 isoform Oryza sativa Japonica Group
1.2.1.44 CCR7 isoform Oryza sativa Japonica Group
1.2.1.44 cinnamoyl CoA reductase
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 Oryza sativa Japonica Group

General Information

EC Number General Information Comment Organism
1.2.1.44 malfunction truncated enzyme lines (CCR-3, CCR-7 and CCR-12) show marked reduction in guaiacyl lignin which is reduced by 10.2% in both CCR-3 and CCR-7, and 9.3% in CCR-12. The down-regulation of lignin leads to significant increase in total phenolics content than the wild type control Oryza sativa Japonica Group