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Literature summary extracted from

  • Mesquita, A.; Tabara, L.C.; Martinez-Costa, O.; Santos-Rodrigo, N.; Vincent, O.; Escalante, R.
    Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase (2015), Open Biology, 5, 150088 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.2.1.1 expressed in HEK-293T cells and Dictyostelium discoideum Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.2.1.1 Mg2+ 5 mM used in assay conditions Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.2.1.1 D-ribose 5-phosphate + D-xylulose 5-phosphate Homo sapiens
-
 sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.1 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.2.1.1 D-ribose 5-phosphate + D-xylulose 5-phosphate
-
 Homo sapiens sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
 r
2.2.1.1 additional information the enzyme interacts with the Atg1 kinase complex Homo sapiens ?
-
-

Subunits

EC Number Subunits Comment Organism
2.2.1.1 ? x * 73000, HA-tagged enzyme, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.2.1.1 TKT
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.2.1.1 thiamine diphosphate
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
2.2.1.1 metabolism the enzyme is fundamental in the non-oxidative branch of the pentose phosphate pathway Homo sapiens