EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.220 | expression in Escherichia coli, N-terminally His6-tagged protein | Hypericum perforatum |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.220 | 0.0013 | - |
benzoyl-CoA | pH 7.0, 35°C | Hypericum perforatum |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.220 | 3 malonyl-CoA + benzoyl-CoA | Hypericum perforatum | - |
4 CoA + 2,4,6-trihydroxybenzophenone + 3 CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.220 | Hypericum perforatum | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.220 | endodermis | of the root | Hypericum perforatum | - |
2.3.1.220 | exodermis | of the root | Hypericum perforatum | - |
2.3.1.220 | root | localized to the exodermis and the endodermis | Hypericum perforatum | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.220 | 3 malonyl-CoA + 3-hydroxybenzoyl-CoA | 43.5% of the activity compared to benzoyl-CoA | Hypericum perforatum | 4 CoA + 2,3',4,6-tetrahydroxybenzophenone + 3 CO2 | - |
? | |
2.3.1.220 | 3 malonyl-CoA + benzoyl-CoA | - |
Hypericum perforatum | 4 CoA + 2,4,6-trihydroxybenzophenone + 3 CO2 | - |
? | |
2.3.1.220 | 3 malonyl-CoA + butyryl-CoA | formation of 36.8% 2,4,6-trihydroxybutyrophenone and 6-propyl-4-hydroxy-2-pyrone as side product | Hypericum perforatum | 4 CoA + 2,4,6-trihydroxybutyrophenone + 6-propyl-4-hydroxy-2-pyrone + 3 CO2 | - |
? | |
2.3.1.220 | 3 malonyl-CoA + isobutyryl-CoA | formation of 46.4% 2,4,6-trihydroxyisobutyrophenone and 34.2% 6-isopropyl-4-hydroxy-2-pyrone as side product | Hypericum perforatum | 4 CoA + 2,4,6-trihydroxyisobutyrophenone + 3 CO2 | - |
? | |
2.3.1.220 | additional information | the enzyme does not accept 2-hydroxybenzoyl-CoA and 4-hydroxybenzoyl-CoA, acetyl-CoA, and CoA esters of cinnamic acids | Hypericum perforatum | ? | - |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.220 | BPS | - |
Hypericum perforatum |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.3.1.220 | 35 | - |
- |
Hypericum perforatum |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.220 | 0.0046 | - |
benzoyl-CoA | pH 7.0, 35°C | Hypericum perforatum |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.3.1.220 | 7 | - |
- |
Hypericum perforatum |