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Literature summary extracted from

  • Wu, R.; Zhang, F.; Liu, L.; Li, W.; Pichersky, E.; Wang, G.
    MeNA, controlled by reversible methylation of nicotinate, is an NAD precursor that undergoes long-distance transport in Arabidopsis (2018), Mol. Plant, 11, 1264-1277 .
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.1.B119 0.004
-
 S-adenosyl-L-methionine pH 7.0, 23°C Arabidopsis thaliana
2.1.1.B119 0.0162
-
 nicotinate pH 7.0, 23°C Arabidopsis thaliana

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.1.1.B119 additional information enzyme is not significantly stimulated by the presence of various metal ions Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.B119 Arabidopsis thaliana Q0WL44 there exist 4 alternatively spliced products
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.B119 root highest expression level Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.B119 additional information no substrates: pyridine-2-carboxylic acid and 2,3-pyridinedicarboxylic acid Arabidopsis thaliana ?
-
-
2.1.1.B119 S-adenosyl-L-methionine + benzoic acid 2% of the activity with nicotinate Arabidopsis thaliana S-adenosyl-L-homocysteine + benzoic acid methyl ester
-
 ?
2.1.1.B119 S-adenosyl-L-methionine + isonicotinate 4.2% of the activity with nicotinate Arabidopsis thaliana S-adenosyl-L-homocysteine + isonicotinic acid methyl ester
-
 ?
2.1.1.B119 S-adenosyl-L-methionine + nicotinate
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + nicotinic acid methyl ester
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.B119 At5g04370
-
 Arabidopsis thaliana
2.1.1.B119 NaMT1
-
 Arabidopsis thaliana

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.B119 6.5 7
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
2.1.1.B119 Arabidopsis thaliana exogenous nicotinic acid methyl ester, nicotinate and nicotinamide treatment does not obviously affect the transcript levels of NaMT1 additional information
2.1.1.B119 Arabidopsis thaliana abiotic stress (salt, abscisic acid, and mannitol) treatments induce the expression of NaMT1 up

General Information

EC Number General Information Comment Organism
2.1.1.B119 physiological function the transfer of nictotinic acid methyl ester from the root to leaf is significantly increased in both methyl esterase MES2 knockdown and NaMT1-overexpressing lines. NaMT1-overexpressing plants have longer roots than wild-type plants under nicotinic acid treatment Arabidopsis thaliana