Literature summary extracted from

Bernstein, H.G.; Dobrowolny, H.; Keilhoff, G.; Steiner, J.
In human brain ornithine transcarbamylase (OTC) immunoreactivity is strongly expressed in a small number of nitrergic neurons (2017), Metab. Brain Dis., 32, 2143-2147 .

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.1.3.3	carbamoyl phosphate + L-ornithine	Homo sapiens	-	phosphate + L-citrulline	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.3.3	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.3.3	brain	the enzyme is expressed in a small number of nitrergic neurons	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.3.3	carbamoyl phosphate + L-ornithine	-	Homo sapiens	phosphate + L-citrulline	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.3.3	ornithine transcarbamylase	-	Homo sapiens
2.1.3.3	OTC	-	Homo sapiens

General Information

EC Number	General Information	Comment	Organism
2.1.3.3	metabolism	the enzyme activity supports nitric oxide production in nitrergic neurons	Homo sapiens

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Release 2023.1 (January 2023)