EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.75 | expressed in Saccharomyces cerevisiae | Mus musculus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.75 | 11-cis-retinyl acetate | the presence of 11-cis-retinyl acetate leads to reduction in esterification of 9-cis-retinol | Mus musculus | |
2.3.1.75 | 11-cis-retinyl laurate | the presence of 11-cis-retinyl laurate leads to reduction in esterification of 9-cis-retinol | Mus musculus | |
2.3.1.75 | 11-cis-retinyl palmitate | the presence of 0.01 mM 11-cis-retinyl palmitate significantly reduces the amount of 9-cis-retinyl ester produced by the enzyme. 11-cis-retinyl palmitate also inhibits13-cis- and all-trans-retinol esterification, but has no effect on formation of 11-cis-retinyl myristate | Mus musculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.75 | 0.02359 | - |
all-trans-retinol | at pH 7.0 and 37°C | Mus musculus | |
2.3.1.75 | 0.02376 | - |
9-cis-retinol | at pH 7.0 and 37°C | Mus musculus | |
2.3.1.75 | 0.02622 | - |
11-cis-retinol | at pH 7.0 and 37°C | Mus musculus | |
2.3.1.75 | 0.03518 | - |
13-cis-retinol | at pH 7.0 and 37°C | Mus musculus | |
2.3.1.75 | 0.04898 | - |
Tetradecanol | at pH 7.0 and 37°C | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.75 | membrane | - |
Mus musculus | 16020 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.75 | acyl-CoA + a long-chain alcohol | Mus musculus | - |
CoA + a long-chain ester | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.75 | Mus musculus | Q6E1M8 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.75 | glutathione-Sepharose column chromatography and Superdex S200 gel filtration | Mus musculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.75 | eye | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.75 | acyl-CoA + a long-chain alcohol | - |
Mus musculus | CoA + a long-chain ester | - |
? | |
2.3.1.75 | myristoyl-CoA + 11-cis-retinol | preferred substrate | Mus musculus | 11-cis-retinyl myristate + CoA | - |
? | |
2.3.1.75 | myristoyl-CoA + 13-cis-retinol | - |
Mus musculus | 13-cis-retinyl myristate + CoA | - |
? | |
2.3.1.75 | myristoyl-CoA + 9-cis-retinol | - |
Mus musculus | 9-cis-retinyl myristate + CoA | - |
? | |
2.3.1.75 | myristoyl-CoA + all-trans-retinol | - |
Mus musculus | all-trans-retinyl myristate + CoA | - |
? | |
2.3.1.75 | myristoyl-CoA + tetradecanol | - |
Mus musculus | tetradecanyl myristate + CoA | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.3.1.75 | ? | x * 35000, SDS-PAGE | Mus musculus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.75 | acyl-CoA wax alcohol acyltransferase 2 | - |
Mus musculus |
2.3.1.75 | AWAT2 | - |
Mus musculus |
2.3.1.75 | MFAT | - |
Mus musculus |
2.3.1.75 | multifunctional O-acyltransferase | - |
Mus musculus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.75 | 0.0042 | 0.0045 | 11-cis-retinyl palmitate | at pH 7.0 and 37°C | Mus musculus |