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Literature summary extracted from

  • Davey, L.; Ng, C.; Halperin, S.; Lee, S.
    Functional analysis of paralogous thiol-disulfide oxidoreductases in Streptococcus gordonii (2013), J. Biol. Chem., 288, 16416-16429 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.8.4.15 expressed in Escherichia coli BL21(DE3) cells Streptococcus gordonii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.4.15 a [DsbA protein] carrying a disulfide bond + N-acetylmuramidase/lysin AtlS Streptococcus gordonii autolysin AtlS requires the enzyme for the formation of an intramolecular disulfide bond between residues Cys1048 and Cys1069. This bond is essential for processing and enzymatic activity ?
-
?
1.8.4.15 a [DsbA protein] carrying a disulfide bond + N-acetylmuramidase/lysin AtlS Streptococcus gordonii SecCR1 autolysin AtlS requires the enzyme for the formation of an intramolecular disulfide bond between residues Cys1048 and Cys1069. This bond is essential for processing and enzymatic activity ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.8.4.15 Streptococcus gordonii
-
-
-
1.8.4.15 Streptococcus gordonii SecCR1
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.4.15 a [DsbA protein] carrying a disulfide bond + N-acetylmuramidase/lysin AtlS autolysin AtlS requires the enzyme for the formation of an intramolecular disulfide bond between residues Cys1048 and Cys1069. This bond is essential for processing and enzymatic activity Streptococcus gordonii ?
-
?
1.8.4.15 a [DsbA protein] carrying a disulfide bond + N-acetylmuramidase/lysin AtlS autolysin AtlS requires the enzyme for the formation of an intramolecular disulfide bond between residues Cys1048 and Cys1069. This bond is essential for processing and enzymatic activity Streptococcus gordonii SecCR1 ?
-
?

Synonyms

EC Number Synonyms Comment Organism
1.8.4.15 SdbA
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Streptococcus gordonii
1.8.4.15 Streptococcus disulfide bond protein A
-
Streptococcus gordonii
1.8.4.15 TDOR
-
Streptococcus gordonii
1.8.4.15 thiol-disulfide oxidoreductase
-
Streptococcus gordonii

General Information

EC Number General Information Comment Organism
1.8.4.15 metabolism the enzyme is required for production of disulfide-bonded proteins Streptococcus gordonii